Allan Johnston
Managing Director & Co-Founder
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- Full Name
- Allan Johnston, Ph.D.
- Title
- Co-Founder & Managing Director
- Firm
- Synergy Ventures (and affiliate Synergy Partners International)
- Firm Type
- Specialist medical-device venture fund investing at seed/early stage (operates much like an early-stage angel/micro-VC in medtech)
- Investment Stage
- Seed and early stage
- Check Size
- $250K to $1M initial investment
- Target Company Profile
- Startups with novel, typically single-use medical devices/diagnostics that can demonstrate clinical efficacy early, advance with lean teams and modest capital, and have strong strategic-partnership or acquisition potential
- Sector Focus
- Medical devices and diagnostics addressing major age-related diseases — cardiovascular, neurovascular/stroke, oncology, orthopedic, respiratory, and gastrointestinal conditions
- Geographic Focus
- U.S.-based medical device startups, with a distinctive angle in facilitating strategic partnerships in Japan
- Location
- Menlo Park, California (545 Middlefield Road, Suite 205, Menlo Park, CA 94025)
Background
Allan Johnston, Ph.D., is a co-founder and managing director of the Synergy Ventures funds and of the affiliated Synergy Partners International, which he helped establish in 1996. The firm is a small, highly specialized medical-technology investor based in Menlo Park, California, focused exclusively on U.S. medical device and diagnostics startups. Under Johnston, Synergy has raised multiple funds (Synergy Ventures II and III appear in institutional databases such as PitchBook) and has been an active early-stage backer in the medtech ecosystem for nearly three decades.
Before founding Synergy, Johnston built a career at the intersection of medical technology, research, and finance. From 1992 to 1996 he was responsible for late-stage private equity investments in medical technology companies at Berkeley International Capital Corporation in San Francisco. From 1987 to 1992 he served as Program Manager at the Center for Medical Technology at SRI International in Menlo Park, where he directed research projects, product development, and technical and business consulting for medical technology companies worldwide — experience that underpins Synergy's hands-on, clinically grounded investing style.
Johnston's training is in the physical sciences: he holds a Ph.D. and an M.Sc. in Inorganic Chemistry from the University of Guelph, Ontario, and an undergraduate degree in Chemistry from Dalhousie University in Nova Scotia. Beyond investing, he has served on the boards of several private companies in Synergy's portfolio and has acted as an outside director for companies commercializing university-developed technology.
Investment Thesis & Focus
- Stage & size: Seed and early-stage medical device deals, writing initial checks of $250K to $1M.
- Sector: Devices and diagnostics for major age-related diseases — cardiovascular, neurovascular/stroke, oncology, orthopedics, respiratory, and GI.
- What makes them say yes: Companies developing "novel, single-use medical devices that can provide clinically efficacious therapy, at lower cost." They prioritize ventures that can demonstrate clinical efficacy early with minimal infrastructure and head-count.
- Exit orientation: Explicitly targets companies with "strong potential for partnership and acquisition" — the thesis is oriented toward strategic M&A (and occasionally IPO) rather than building standalone companies.
- Differentiated value-add: Helps portfolio companies form corporate partnerships in Japan, drawing on Japan-based medical-device corporations among its limited partners.
Notable Investments
- Paradromics — high-bandwidth neural interface ("Connexus") brain-computer interface company.
- Neptune Medical — dynamically rigidizing overtube technology for endoscopy.
- Aria CV — implantable device for pulmonary hypertension.
- Cagent Vascular — serration angioplasty for peripheral artery disease.
- Inquis Medical — catheters for pulmonary embolism / DVT.
- NeoCis — "Yomi" robotic guidance system for dental implants (FDA-cleared 2017).
- Autonomix, Neptune, NeuroSave, Palmera Medical, Pulson, Respirix, RODO Medical, Savage Medical, ThrombX Medical — additional cardiac, neurovascular, and interventional device holdings.
- Intuitive Surgical — robotic-assisted surgery; IPO 2000.
- Align Technology — Invisalign; IPO 2001.
- Ultracision — Harmonic Scalpel; acquired by Johnson & Johnson (1995).
- Perclose — arterial closure; IPO 1995, acquired by Abbott (1999).
- Companion Medical — smart insulin pen; acquired by Medtronic (2020).
- DeVoro Medical — peripheral thrombectomy; acquired by Boston Scientific (2021).
- Arrinex — nasal cryotherapy; acquired by Stryker (2019).
- Medina Medical — neurovascular aneurysm implant; acquired by Medtronic (2015).
- Chestnut Medical, CV Ingenuity, C2 Therapeutics, Marblehead Medical, ReliGN, Salient Surgical, Medivance, Amira Medical, Cardiac Pathways, Fox Hollow, Natus Medical, Omnicell, RITA Medical, VidaMed — additional medtech companies acquired by or IPO'd into strategics including Boston Scientific, Medtronic, Stryker, Roche, and C.R. Bard.
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