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Fred Goldwater

Venture Partner

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At a glance

Full Name
Fred Goldwater
Title
Venture Partner
Firm
Hatteras Venture Partners
Firm Type
Healthcare-focused venture capital firm (Fred also serves as an angel/advisor and board member to healthcare companies)
Investment Stage
Pre-seed, Seed, Seed-plus, and Series A
Check Size
~$500,000 to $5 million (firm-level)
Target Company Profile
Early-stage companies built on cutting-edge science, often spun out of leading academic/research institutions, with high-quality teams and potential for significant impact on patient care
Sector Focus
Biopharmaceuticals, medical devices, diagnostics, and healthcare IT
Geographic Focus
North Carolina and the Southeastern United States (with the firm maintaining additional offices in Dallas, Providence, Washington D.C., Allen TX, the San Francisco Bay Area, and Beijing)
Location
Durham, North Carolina, USA

Background

Fred Goldwater has been a Venture Partner at Hatteras Venture Partners since August 2011. He brings more than 40 years of executive-management experience spanning manufacturing, financial services, and healthcare, with a deep background in business development (mergers, acquisitions, joint ventures, and large-scale project implementation), operations, information systems, sales, marketing, and product development. In his role at Hatteras, he provides strategic advisory services and executive support to companies serving the healthcare market.

His operating career includes a long tenure at Blue Cross and Blue Shield of North Carolina, where he held senior roles including SVP of Strategic Development, CIO, and SVP of Operations (with responsibility for self-insured, government, and senior-market segments) before retiring at the end of 2007. He later served as CEO of RealMed, a revenue-cycle-management company, overseeing its sale to Availity. Subsequent operating roles included COO of Community Care of North Carolina Services (Medicaid population-health management), COO of AlignCare Services (an Rx-data analytics company, Dec 2016–Apr 2019), and CEO / Executive Chairman of Gobiquity, Inc. (parent of the GoCheck Kids pediatric vision-screening platform). Earlier in his career he held executive roles at Providian/Capital Holding and WestRock.

Beyond his Hatteras and operating roles, Fred has provided consulting and advisory support to organizations including the NC Health Information Exchange, FastMed, LipoScience, Cain Brothers, American Well, Medfusion, and Technosoft, and he has served as an advisor to Excelerate Health Ventures. He has served on the boards of 410 Medical and the Chamber Orchestra of the Triangle.

Fred earned his undergraduate degree from Babson College and an MBA from Pace University.

Investment Thesis & Focus

  • Invests through Hatteras Venture Partners, which "builds transformational companies" in biopharmaceuticals, medical devices, diagnostics, healthcare IT, and related human-medicine opportunities.
  • Backs early-stage healthcare companies typically built on "high-quality science and teams with the potential for significant impact on patient care," frequently sourced from leading academic institutions.
  • Stage focus spans pre-seed through Series A; the firm writes checks generally in the ~$500K–$5M range.
  • Emphasizes research-driven but historically undercapitalized regions, with a strong bias toward North Carolina and the Southeastern U.S.
  • Fred's personal value-add skews toward healthcare-services, operations, revenue-cycle, health IT, and commercialization — reflecting his operating background running healthcare payer, provider-services, and digital-health businesses.

Notable Investments

  • G1 Therapeutics — oncology biopharma; completed its IPO in 2017.
  • HistoSonics — medical-device company (histotripsy platform); reported acquisition valued at ~$2.25 billion.
  • Kymera Therapeutics — targeted-protein-degradation biotech; publicly traded.
  • 410 Medical — critical-care/resuscitation medical device company (Fred has served on its board).
  • Jumo Health — patient-education/health-content company; acquired in 2024.
  • Iris Healthcare — advance-care-planning company; acquired by Aledade (2023).
  • Atsena Therapeutics — gene-therapy company for inherited retinal disease.
  • Aer Therapeutics, Cardiosense — additional healthcare/therapeutics portfolio companies.
  • Gobiquity / GoCheck Kids — pediatric vision-screening platform Fred led as CEO/Executive Chairman.

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