
Jens Eckstein
Managing Partner
Get their honest, personalized take on your startup.
Sign in to pitch Jens →At a glance
- Full Name
- Dr. Jens W. Eckstein
- Title
- Managing Partner (Apollo Health Ventures); now Investment Partner at Hevolution Foundation
- Firm
- Apollo Health Ventures (advisory board); Hevolution Foundation
- Firm Type
- Life-science venture capital / institutional longevity fund (often acting as an angel and venture creator)
- Investment Stage
- Seed and early-stage; venture creation (company building)
- Check Size
- Not publicly disclosed (Apollo Fund II is $180M, used across seed/early-stage and venture creation)
- Target Company Profile
- Data-driven, science-led biotech and health-tech startups built around the biology of aging and age-related disease; frequently companies he co-founds or builds from scratch
- Sector Focus
- Aging/longevity biology, geroscience, breakthrough therapeutics, drug discovery, healthcare IT/data
- Geographic Focus
- Transatlantic — Europe and the United States
- Location
- Boston, USA (with Apollo offices in Berlin, Luxembourg, and Boston)
Background
Dr. Jens Eckstein is a life-science investor and company builder with more than 25 years in biopharma venture capital and roughly a decade of operational experience in drug discovery and development. He earned a Diploma in Chemistry from the University of Konstanz (1987) and a Ph.D. in Biological Chemistry from Harvard University (1991), and is a Kauffman Fellow and a member of the EU-sponsored Gold Track Expert Council.
His most prominent prior role was President of SR One, GlaxoSmithKline's corporate venture fund, where he spent roughly eight years. Under his leadership the SR One team deployed over $500 million and was involved in 18 IPOs — including CRISPR Therapeutics, Turning Point (TP) Therapeutics, and Principia Biopharma — as well as 12 M&A transactions. He was also co-founder and Managing Director of Action Potential Venture Capital (APVC), a pioneering fund for bioelectronic medicines, and earlier a general partner in TVM Capital's Boston life-sciences practice focused on early-stage investing.
In 2019 he joined Apollo Health Ventures as Managing Partner. Apollo is an early-stage transatlantic life-science fund investing exclusively in breakthrough therapeutics arising from the biology of aging; in December 2021 it closed a $180 million (€157.5M) second fund to back data-driven biotech and health-tech ventures targeting age-related disease. At Apollo he was a prolific venture builder, holding the chairmanship or board seat of multiple portfolio companies. He is now listed as an Advisory Board member at Apollo.
More recently, Dr. Eckstein became an Investment Partner at the Hevolution Foundation, a Riyadh-headquartered, Saudi-backed global non-profit with an annual budget of up to $1 billion — one of the largest funders of healthy-aging and geroscience research and translation worldwide.
Investment Thesis & Focus
- Invests at seed and early stage, and frequently as a venture creator — co-founding and building companies rather than only writing passive checks.
- Core thesis is the biology of aging: backing breakthrough therapeutics and platforms that target aging pathways (autophagy, mitophagy, senescence) to treat age-related disease and extend healthspan.
- Favors data-driven, deeply science-led teams — companies translating rigorous academic biology into drug-discovery programs.
- Geographic focus is transatlantic (Europe + US), reflecting Apollo's Berlin/Luxembourg/Boston footprint.
- On the Vandria investment he framed deals around alignment with "Hevolution's mission to fund innovations in healthy aging" — a signal that mission fit with longevity/healthspan science is a gating criterion.
Notable Investments
- Samsara Therapeutics — autophagy-focused aging/longevity drug discovery company; Eckstein served as Chairman/President.
- Booster Therapeutics — therapeutics startup; Eckstein served as Chairman.
- Refoxy Pharma — aging-biology therapeutics; Eckstein served as Chairman.
- Aeovian Pharmaceuticals — mTOR-selective therapeutics; board director.
- HAYA Therapeutics — RNA-based precision medicine for fibrosis/age-related disease; completed a CHF 18M seed financing; board director.
- Cleara Biotech — senolytics / senescent-cell-targeting company; board director.
- Vandria — mitophagy inducer (VNA-318) for CNS; Hevolution joined a ~$30.7M (CHF 28.3M) Series A closing in 2024.
- SR One era (as President): CRISPR Therapeutics, Turning Point (TP) Therapeutics, and Principia Biopharma (all reached IPO).
Unlock the full research
Get how to approach them, recent activity, sources, contact links — plus pitch their AI twin for a candid read on your raise.
One-time. Stays unlocked for you.