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Katleen Vandersmissen
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Katleen Vandersmissen

Managing Partner

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At a glance

Full Name
Katleen Vandersmissen
Title
Managing Partner & Co-Founder
Firm
HERAN Partners
Firm Type
Venture Capital (healthtech/medtech specialist) — also active as an angel/early-stage investor
Investment Stage
Seed and Series A
Check Size
Up to ~€5 million in early-stage companies
Target Company Profile
Start-ups and scale-ups with a solid technology platform, a strong scientific and entrepreneurial team, and real-world applicability in healthcare settings (software, hardware, and services)
Sector Focus
HealthTech, MedTech, digital health, life sciences, deep tech, diagnostics, medical imaging/AI, and drug-discovery technology
Geographic Focus
Europe (notably Belgium, the Netherlands, the UK, and Spain)
Location
Antwerp, Belgium

Background

Katleen Vandersmissen is a co-founder and Managing Partner of HERAN Partners, a Belgian healthtech-focused venture capital firm based in Antwerp. She holds a PhD in Chemistry and began her career in industry, heading one of the R&D and quality-assurance labs at Umicore, the Belgian materials-technology group. She subsequently moved into strategy consulting at McKinsey & Company, where she focused on strategy and M&A work.

Before co-founding HERAN, Katleen spent roughly seven years at the Belgian institutional investor LRM, where she served as investment manager and head of the Health & Care department. That role gave her deep, hands-on exposure to the life-sciences start-up and scale-up ecosystem and formed the foundation for her transition into dedicated healthcare venture investing.

In 2020 she co-founded HERAN Partners alongside Annie Vereecken, Joris Mortelmans, and Herman Verrelst, with a mandate centered on MedTech and digital health. At HERAN she is responsible for the firm's general management and long-term strategy, fundraising, final investment decisions, and oversight of several portfolio companies. HERAN's first fund closed at €75.5 million and backed 15 companies across Belgium, the Netherlands, and the UK; in February 2026 the firm announced a €90 million first close of its second fund (HERAN HealthTech Fund II), targeting €110–120 million.

Investment Thesis & Focus

  • Stage & ticket: Invests primarily at Seed and Series A, with tickets of up to ~€5 million per early-stage company.
  • Sector conviction: Concentrated bet on European healthtech and medtech — diagnostics, medical imaging and AI, drug-discovery technology, surgical tech, women's health, and healthcare data/real-world-evidence platforms.
  • Team-first: Repeatedly emphasizes backing "a strong team with scientific and entrepreneurial expertise," and seeks founders who are "tough, intelligent, perseverant and possess high levels of genuine positivity."
  • Real-world impact over data accumulation: On Fund II she framed the thesis as: *"Technology should support clinicians and researchers — not overload them"* — favoring solutions that generate better healthcare insight and are implementable in real clinical settings, spanning software, hardware, and services.
  • Relationship-driven: Stresses that "personal relationships in venture capital" are crucial; HERAN builds reach across Europe through syndication, co-investment partnerships, and industry conferences.
  • Personal mantra: Quotes Edison — *"Many of life's failures are people who did not realize how close they were to success when they gave up."*

Notable Investments

  • Aspect Analytics — Bioinformatics software for spatial-omics data; HERAN participated in its Series A (announced September 2025).
  • Gynaia — Women's-health diagnostics using AI in gynecologic oncology; raised a €2.3M seed round co-led by HERAN Partners and Gemma Frisius Fund (2025).
  • Thirona — AI-assisted medical image analysis in pulmonary and ophthalmology; HERAN backed a financing round (with Borski Fund, 2021).
  • LynxCare — Real-world-evidence data hubs built on NLP over structured and unstructured healthcare data.
  • icometrix — Software extracting clinically meaningful data from brain MRI for neurological conditions.
  • ONTOFORCE — Semantic search/data-linking technology for enterprise life-sciences research.
  • Hypervision Surgical (UK) — AI and hyperspectral/edge imaging to assess tissue status during surgery.
  • Broken String Biosciences — Genome-stability assessment for safer cell and gene therapies.
  • Pharmacelera (Spain) — In-silico drug-discovery technology.
  • Fluidic Sciences (UK) — High-performance microfluidics platforms for biologics discovery.
  • ImmuneSpec, Nuclivision, Amaron, FOx Biosystems (now VixenBio) — additional portfolio holdings in immunogenicity testing, nuclear-medicine imaging, healthcare data integration, and fiber-optic biosensing.
  • Exits: BlueBee (acquired by Illumina), PharmaFluidics (acquired by Thermo Fisher), and UgenTec (acquired by Summa Equity).

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