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Krishna Yeshwant
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Krishna Yeshwant

Managing Partner

Angel InvestorsSeed Round
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At a glance

Full Name
Krishna Yeshwant, MD
Title
Managing Partner
Firm
GV (formerly Google Ventures)
Firm Type
Corporate / institutional venture capital (Alphabet is sole LP)
Investment Stage
Seed, Series A, Series B and later
Check Size
~$250K to $50M (per aggregator data; varies by stage)
Target Company Profile
Science- and technology-driven healthcare and biotech companies, from early incubation through growth; teams building at the intersection of biology, software, and clinical care
Sector Focus
Life sciences and healthcare — therapeutics, biotech, diagnostics, medical devices, health IT, care delivery, payor/provider, and AI in healthcare
Geographic Focus
Primarily United States (with activity across Canada and Europe)
Location
Boston, Massachusetts

Background

Krishna Yeshwant is a Managing Partner at GV, where he co-leads the firm's life sciences group. He occupies a rare dual role, remaining an active internal medicine attending physician at Brigham and Women's Hospital in Boston while investing — giving him a frontline clinician's perspective alongside his venture work. The son of two Chicago physicians, his first love was actually computing: he majored in computer science at Stanford and, before medicine, co-founded two successful technology startups — an electronic data interchange company acquired by Hewlett-Packard and a network security company acquired by Symantec.

His path into medicine began around 2002, when he worked with surgeons at Massachusetts General Hospital and Brigham and Women's Hospital to write software that used imaging systems to guide surgical procedures. He went on to earn a combined MD/MBA from Harvard (Harvard Medical School and Harvard Business School) and completed his internal medicine residency at Brigham and Women's.

Yeshwant joined Google in 2008 and was part of the small team involved in GV's founding, where he championed and led the fund's early commitment to investing in life sciences — at a time when few generalist venture firms were building dedicated biotech practices. Today he helps steward the broader GV investing team and has built out the firm's life sciences incubation program, launching companies from the ground up rather than only backing existing ones.

Investment Thesis & Focus

  • Invests across the full healthcare spectrum: care delivery, health IT, devices, diagnostics, payor/provider models, and therapeutics.
  • Bridges biology and patient-facing software — pairing deep science with his own clinical experience and Google's early business-development playbook.
  • Advocate for "new long-horizon science funding models," arguing (as he told Fortune) that the traditional way science is funded "is crazy" and needs rethinking for ambitious, curative research.
  • In his own words on the current moment in biotech: *"We're in an era where we can see a path to not just treating, but curing more diseases."*
  • Comfortable with risk and long time horizons — GV deploys large amounts of capital annually into scientifically risky bets, and Yeshwant both incubates new companies and invests at seed through growth stages.

Notable Investments

  • Flatiron Health — oncology data/health-IT company; led early; acquired by Roche (2018).
  • Foundation Medicine — cancer genomic diagnostics; early GV backing; acquired by Roche.
  • Relay Therapeutics — precision oncology / protein-motion drug discovery; public (RLAY).
  • Beam Therapeutics — base-editing genetic medicines; public (BEAM).
  • insitro — machine-learning-driven drug discovery.
  • One Medical — tech-enabled primary care; acquired by Amazon (2023).
  • Aledade — value-based primary care enablement for independent physicians.
  • Verve Therapeutics — gene-editing for cardiovascular disease; GV incubation; acquired by Eli Lilly.
  • ROME Therapeutics — "dark genome" / repeatome-focused therapeutics; GV incubation.
  • Also associated with GV bets including Isomorphic Labs, Neuralink, DNAnexus, Cala Health, and Aspen Neuroscience.

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