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Kristina Shen

General Partner

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At a glance

Full Name
Kristina Shen
Title
Co-Founder & Managing Partner (formerly General Partner, Andreessen Horowitz)
Firm
Chemistry (chemistry.vc)
Firm Type
Venture Capital (early-stage)
Investment Stage
Seed and Series A (leads rounds)
Check Size
Leads seed/Series A rounds out of a $350M debut fund; each partner makes ~2–3 high-conviction investments per year. (Historical individual deal range while at a16z was roughly $500K–$40M, sweet spot ~$20M per Signal/NFX data.)
Target Company Profile
Standout early-stage software companies the firm can lead and concentrate behind
Sector Focus
B2B / enterprise software — SaaS, fintech, infrastructure, developer tools, and "work software" / vertical SaaS
Geographic Focus
Primarily United States
Location
San Francisco, California

Background

Kristina Shen is a co-founder and Managing Partner of Chemistry, an early-stage venture firm she launched in October 2024 alongside Ethan Kurzweil (ex-Bessemer) and Mark Goldberg (ex-Index Ventures). The firm debuted with a $350M Fund 1 dedicated to leading a concentrated set of high-conviction seed and Series A investments in software. Their pitch is structural alignment with founders — the three GPs describe themselves as a "lean" firm that personally works "in the trenches" rather than scaling like legacy platforms, citing a collective track record of leading early investments in more than a dozen unicorns and serving on 50+ boards.

Before Chemistry, Shen spent about four years (joining December 2019) as a General Partner at Andreessen Horowitz, where she led the firm's B2B / enterprise software investing practice, covering everything from developer tooling and core infrastructure to non-traditional vertical SaaS. Prior to a16z, she spent roughly seven years at Bessemer Venture Partners, where she became a Partner working on cloud and SaaS investments and co-authored Bessemer's widely read "State of the Cloud" report and Cloud Index. She held board roles at SaaS companies including ServiceTitan and Gainsight during her Bessemer tenure.

Earlier in her career, Shen worked in technology investment banking at Goldman Sachs and Credit Suisse — where she worked on IPOs of companies such as Palo Alto Networks, Zynga, Fusion-io, and Infoblox — and was an associate at growth-equity firm JMI Equity, focused on sourcing software investments. She earned a B.A. in Operations Research & Management Science from the University of California, Berkeley. She is widely recognized in the industry for a rigorous, metrics-driven approach to SaaS analysis (cohorts, net dollar retention, unit economics). She is a mother of three.

Investment Thesis & Focus

  • Stage: Leads seed and Series A rounds; concentrated, high-conviction model (each partner does only ~2–3 deals/year).
  • Sectors: B2B/enterprise software broadly — SaaS, fintech, infrastructure, developer tools, and vertical/"work" software. At a16z she focused on enterprise SaaS, core infrastructure, horizontal middleware, and developer tooling.
  • Core philosophy (Chemistry): "What would a venture firm look like if its success was fully aligned with its founders' success?" The partners position themselves as the portfolio-services team, bringing "founder energy" and deep personal involvement rather than scale.
  • What makes her say yes: A reputation for "phenomenal" SaaS-metrics analysis — she scrutinizes cohorts, retention/NDR, and durable unit economics, and has a documented thesis on how AI is reshaping the SaaS landscape (a recurring theme in her SaaStr talks).
  • Style: Described in a16z's announcement as "one of the top analytical minds in the industry," with a strong stated commitment to entrepreneurs.

Notable Investments

  • ServiceTitan — Vertical SaaS for the trades / home-services; Bessemer-era board seat; IPO'd December 2024.
  • Gainsight — Customer-success software platform (Bessemer era).
  • Tennr — Healthcare referral/workflow automation; a16z-led investment.
  • Equals — Modern, connected spreadsheet/analytics tool; a16z-led.
  • Matik — Data-driven content/personalization automation; a16z-led.
  • Mux — Video streaming/API infrastructure for developers.
  • Pave — Compensation benchmarking and planning software (Series A).
  • Wrapbook — Payroll and production-management software for film/entertainment (Series A).
  • Decagon — AI customer-support agents.
  • Assort Health — AI for healthcare patient communications (later-stage rounds).
  • Didero — AI-driven procurement / supply-chain software (Series A).
  • Sprig, Macro, Serval — Additional B2B software portfolio companies listed on her Chemistry profile.

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