Lindsay Avagliano
Principal
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- Full Name
- Lindsay Freeman Avagliano
- Title
- Principal (former), Prolog Ventures; currently Co-Founder & COO, CivicReach
- Firm
- Prolog Ventures
- Firm Type
- Venture capital (health, wellness & sustainability focused) — note the stub's "Angel Investors" label is inaccurate; Prolog is an institutional VC fund
- Investment Stage
- Pre-seed and Seed through early growth
- Check Size
- ~$500K–$5M initial, up to ~$10M with follow-on (firm-level)
- Target Company Profile
- Early-stage startups improving healthy living and a sustainable world; she has publicly emphasized backing teams with prior founder experience
- Sector Focus
- Food & beverage, nutrition, personal & household care, consumer wellness, agriculture technology, diagnostics, and infection control
- Geographic Focus
- United States
- Location
- Chapel Hill / Raleigh–Durham, North Carolina (Prolog Ventures is headquartered in Clayton, Missouri)
Background
Lindsay Freeman Avagliano is an executive with roughly 15 years of experience working at the intersection of technology, law, and venture finance. She earned a J.D. from the University of Chicago Law School (2007–2010) and began her career as a startup and venture-finance attorney at law firms in New York City and Raleigh, including Smith Anderson. That legal grounding in emerging-company and corporate work has been a through-line across her subsequent roles in venture capital and operations.
At Prolog Ventures — a St. Louis-area fund dedicated to companies that promote healthy living and a sustainable world — she served as a Principal (having joined earlier as a Senior Associate). In that role she led and supported investments in the firm's health, wellness, and infection-control themes. Most notably, she led CleanSlate UV's $7 million Series A in April 2020 and joined its board of directors alongside Prolog's Rob Rosenberg, deploying capital from the Prolog Lonza fund focused on infection control and prevention.
After Prolog, she moved deeper into venture and operating roles, including a stint as Director of New York Ventures (the early-stage venture fund backed by New York State's economic-development agency, Empire State Development). In 2024 she co-founded CivicReach with CEO Chip Kennedy, where she serves as Chief Operating Officer. CivicReach, based in Raleigh, builds a conversational voice-AI "virtual front desk" that helps understaffed local governments and municipalities handle constituent calls and service requests. She is also listed as an advisor with Astia, an organization supporting women-led high-growth ventures.
Her career therefore spans both sides of the table — as a venture investor and board member, and now as an operating co-founder — which shapes a hands-on, founder-empathetic perspective on early-stage building.
Investment Thesis & Focus
- Mission lens: At Prolog Ventures, invests behind companies advancing "healthy living and a sustainable world" — food & beverage, nutrition, personal/household care, consumer wellness, ag-tech, and diagnostics.
- Stage & checks (firm-level): Pre-seed to early growth; initial checks roughly $500K–$5M, with follow-on capacity up to ~$10M.
- Infection control conviction: On the CleanSlate UV deal she stated, "Infection control and prevention is a critical focus area for the Prolog Lonza fund. We are excited to work with the CleanSlate UV team to combat the spread of infection in healthcare and other commercial settings."
- Values founder experience: In a published interview ("The Significance of Previous Founder Experience"), she highlighted prior founder/operator experience as a meaningful signal when evaluating startup teams.
- Board-level engagement: Willing to take active board roles post-investment (e.g., CleanSlate UV), reflecting a hands-on rather than passive approach.
Notable Investments
- CleanSlate UV — Chemical-free, UV-light hospital-grade mobile-device sanitizers; Prolog led its $7M Series A (April 2020) and she joined the board.
- Prolog Ventures portfolio (firm-level, illustrative of the strategy she worked within):
- Spindrift — Sparkling water made with real squeezed fruit.
- Plum Organics — Squeezable organic baby-food pouches (acquired).
- Benson Hill — Food/ag genetics and supply-chain platform (went public via IPO).
- Veran Medical Technologies — Earlier-diagnosis medical technology (acquired).
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