
Sarah Meibusch
Principal
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- Full Name
- Sarah Meibusch
- Title
- Partner, Head of Healthcare
- Firm
- OneVentures
- Firm Type
- Venture capital
- Investment Stage
- Clinical-stage healthcare companies; Series A and more often Series B, with OneVentures’ healthcare mandate requiring companies to be clinical stage or less than a year from first-in-human studies
- Check Size
- A$10 million to A$25 million for equity investments, according to Meibusch’s Bionics Institute interview
- Target Company Profile
- Privately owned, unlisted healthcare companies developing first-in-class or best-in-class products or technologies for large unmet medical needs, with quality science, clear regulatory and reimbursement paths, and global commercial potential
- Sector Focus
- Life sciences, therapeutics, biotechnology, medical devices, diagnostics, digital health, healthcare technology
- Geographic Focus
- Australia-originated healthcare innovation with global markets; OneVentures also syndicates internationally and has backed U.S.-based companies
- Location
- Brisbane, Australia
Background
Sarah Meibusch is Partner and Head of Healthcare at OneVentures, where she leads the firm’s healthcare pillar and focuses on sourcing and supporting life sciences companies developing transformative technologies with global potential. OneVentures says she currently serves as Chair of Vaxxas and Axial Therapeutics, a Board Member for Kira Biotech, and an Alternate Board Member and Observer for Clinical Genomics and Prota Therapeutics.
She joined OneVentures in 2017 as an Investment Manager when the firm was building the team for its A$170 million Healthcare Fund III, a fund focused on Australian companies commercialising drugs, medical devices and diagnostics in or near clinical development. She was later promoted to Partner in 2022 and appointed Head of Healthcare in 2026.
Before OneVentures, Meibusch worked across life sciences business development and commercial strategy in Australia and the United States. OneVentures said she had spent five years scouting technologies for Shire Pharmaceuticals across Australia, New Zealand, Singapore, Taiwan, Korea and Japan, including sourcing the Fibrotech transaction. She also held senior roles at Progen Pharmaceuticals, the University of Queensland’s QAAFI institute, Beef CRC and Pyxis Genomics.
Her education includes a Bachelor of Agricultural Science with First Class Honours from the University of Queensland and a master’s degree in genomics from Cornell University. She has post-graduate training in negotiation from Harvard and is a Graduate of the Australian Institute of Company Directors. She is also listed as a member of the QIMR Berghofer Medical Research Institute Commercial Advisory Board and the AusBiotech Investment Advisory Group.
Investment Thesis & Focus
- OneVentures’ healthcare thesis, as stated on its healthcare page, is to back “transformative technology that will deliver best-in-class patient outcomes with global reach and impact.”
- Meibusch said in a Bionics Institute interview that OneVentures backs outstanding teams, sound business models, strong forecasts, global potential and opportunities to disrupt a market.
- For life sciences, she said the technology must be “truly game changing,” either first-in-class or best-in-class, and must address an unmet medical need while fitting the fund mandate and return horizon.
- OneVentures’ healthcare mandate screens for companies that are privately owned and unlisted, clinical stage or less than a year from first-in-human studies, and developing first- or best-in-class products for large unmet medical need.
- Meibusch said OneVentures typically does not invest “super early stage”; for equity investments it needs to deploy enough capital, usually A$10 million to A$25 million, with a first check “maybe a Series A, but more likely a Series B.”
- OneVentures emphasizes milestone-based investing: proof of clinical efficacy and safety, quality science, and a clear regulatory and reimbursement path.
- The firm describes itself as hands-on, supporting portfolio companies with commercialisation strategy, industry connections, governance, capital strategy and global expansion.
Notable Investments
- Vaxxas: Clinical-stage biotechnology company developing a high-density microarray patch for needle-free vaccine delivery; Vaxxas raised approximately A$90 million in 2025, and Meibusch was appointed Chair.
- Kira Biotech: Australian biotechnology company developing immunomodulatory antibody therapies for autoimmune and inflammatory diseases; OneVentures led Kira’s A$20 million Series A in 2019, when Meibusch was a Principal.
- Prota Therapeutics: Late clinical-stage biotech company developing oral immunotherapy for food allergy remission; OneVentures committed A$10 million from Healthcare Fund III after leading the initial A$15 million Series A financing.
- Axial Therapeutics / Vertero Therapeutics: Clinical-stage biopharmaceutical company focused on gut-restricted small-molecule therapies for CNS disorders; OneVentures co-led Axial’s US$37.25 million Series C in 2021, and Meibusch joined the board.
- Clinical Genomics: Diagnostics company in the OneVentures healthcare portfolio; Meibusch lists it among the healthcare companies she has worked with and serves as an alternate board member and observer.
- BiVACOR: Medical device company developing a total artificial heart; OneVentures backed the company through the Biomedical Translation Fund, and Meibusch has publicly cited BiVACOR’s artificial-heart implantation milestone as a highlight of her work.
- Paragen Bio: Cairns-based company developing treatments for autoimmune diseases; OneVentures participated in its first fundraising round through Healthcare Fund III in 2018, and Meibusch appeared in the investment announcement.
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